Tyrell Malacia made his debut for Feyenoord in the 2017-2018 season, after going through all of his youth training at Varkenoord. After 136 games in Rotterdam service, Tyrell was recruited by Manchester United. In his first season, he played 39 games for 'The Red Devils,' but a serious injury stalled his career in England.

Since the winter of 2025, Tyrell has been playing on a rental basis for PSV, where his profile as an emerging left back, fits perfectly with head coach Peter Bosz's game.